Serotonin Syndrome Drugs
Not to be confused with ssri discontinuation syndrome.
Serotonin syndrome drugs. Usually without a fever. Serotonin and norepinephrine reuptake inhibitors snris antidepressants such as duloxetine. A potentially lethal condition serotonin syndrome ss is caused most often when certain antidepressant agents are taken concurrently with other drugs that modulate synaptic serotonin levels. 12 when patients take two or more antidepressants from different pharmacologic classes drug drug interactions may occur.
Some illegal drugs such as lsd and cocaine and dietary supplements including st. Johns wort and ginseng can lead to serotonin syndrome when combined with antidepressants that affect serotonin. The risk of serotonin syndrometoxicity increases if you are also taking other drugs that increase serotonin. Milder forms of serotonin syndrome usually go away within 24 to 72 hours of stopping medications that increase serotonin and by taking medications to block the effects of serotonin already in your system if theyre needed.
These interactions may lead to potentially severe serotonin toxicity or ss. This syndrome was first described during the 1960s in studies of monotherapy and combination therapy. You might be at higher risk if you take two or more drugs andor supplements that affect your serotonin levels. An overdose of a drug that raises serotonin levels prescription drugs to treat depression seizures migraines pain vomiting and parkinson disease even when they are used as directed st johns wort cocaine ecstasy and cough syrup that contains dextromethorphan what are the signs and symptoms of serotonin syndrome.
Nerve cells normally produce serotonin. Its believed to occur when too much serotonin builds up in your body. Symptoms in mild cases include high blood pressure and a fast heart rate. The degree of symptoms can range from mild to severe.
The drugs and supplements that could potentially cause serotonin syndrome include. Serotonin syndrome ss is a group of symptoms that may occur with the use of certain serotonergic medications or drugs. Serotonin syndrome is a potentially serious negative drug reaction. Ask your doctor when to start or stop taking this medication.
Selective serotonin reuptake inhibitors ssris antidepressants such as citalopram celexa fluoxetine prozac. The drugs and supplements that could potentially cause serotonin syndrome include. However symptoms of serotonin syndrome caused by some antidepressants could take several weeks to go away completely.